Mannose-binding lectin and the kidney.

نویسندگان

  • Anja Roos
  • Mohamed R Daha
  • Johannes van Pelt
  • Stefan P Berger
چکیده

et al. Caspase inhibition reduces tubular apoptosis and proliferation and slows disease progression in polycystic kidney disease. Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease. Magenheimer BS et al. Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype. Fujita H et al. Extracellular signal-regulated kinase inhibition slows disease progression in mice with polycystic kidney disease. Increased water intake decreases progression of polycystic kidney disease in the PCK rat. Safety and efficacy of long-acting somatostatin treatment in autosomal-dominant polycystic kidney disease. Larson CH et al. The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease. Tuberin-dependent membrane localization of polycystin-1: a functional link between polycystic kidney disease and the TSC2 tumor suppressor gene. slows disease progression in a rat model of polycystic kidney disease. Intraflagellar transport and cilia-dependent renal disease: the ciliary hypothesis of polycystic kidney disease. A et al. PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2. A, Mulner O et al. Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. arrest of murine polycystic kidney disease with CDK inhibitor roscovitine. A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days. CDK/GSK-3 inhibitors as a new approach for the treatment of proliferative renal diseases.

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عنوان ژورنال:
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

دوره 22 12  شماره 

صفحات  -

تاریخ انتشار 2007